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KMID : 0367419710140030039
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Journal of Korean Pediatric Society
1971 Volume.14 No. 3 p.39 ~ p.45
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Clinical studies of Leukemia in Childhood
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金佐信/Kim, Jwa Sin
劉永祐/孫槿贊/李謹洙/Lieu, Yonng Ho/Sohn, Keun Chan/Lee, Keun Soo
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Abstract
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A total of 74 cases of leukemia in children who were admitted at The National Medical Center from January 1960 to July 1969 were anayaed clinically and hematologically.
1. The incidence of leukemia was about 4 per 1,000 patients who admitted during the same period.
2. Male patients were more prevalent being male to female ratio 2.7:1
3. The 6~7 year old age group showed the highest morbidity (21.6%) with 52.7% in up to 7 years old age.
4. The incidence of the various cytological types was as follows : Acute lymphocytic 40.5%, acute myelocytic 28.2%, undifferentiated leukemia 16%, chronic myelocytic 9%, acute monocytic 5% and erythroleukemia 1.3%.
5. Common chief complaints were pallor (85.1%), fever(71.6%), general weakness(55.5%), bleeding tendency (52.7%), headache(33.8%), abdominal pain and others.
6. Common objective signs were hepatomegaly (64.7%), lymphnode swelling (60.8%), purpura (48.6%), splenomegaly (46%), edema(20.2%) and others.
7. Hemoglobin value below 4G% was found in 10 cases (13.5%), below 6G% in 36 cases (48.6%) and above 10G% in 6 cases (8.1%)
8. Leucoyxte count were variable : 5,000-100,000/㎣ in 15 cases (20.3%). marked leucocytosis (above 50,000/㎣) in 17 cases (22.9%) and leucopenia in 17 cases (22.9%)
9. Platelets were decreased in number and it related closely to bleeding tendency. Marked thrombocytopenia? in 32 cases (45.7%). 50,000-150,000/㎣ in 25 cases (35.7%) and 200,000㎣ ?in 4 cases (7.2%).
A review of literature on the leukemia in childhood was made.
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